NeuroNexus in Ann Arbor Partners to Advance Brain Disorder Treatment

Inscopix Inc., a brain mapping platform company in Palo Alto, Calif., and NeuroNexus Inc., a neurotechnology company pioneering high-capacity implantable neural interfaces in Ann Arbor, announced a collaboration to develop the world’s first integrated electrophysiology and imaging system.
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Index finger pointing at human brain imaging
NeuroNexus in Ann Arbor and Inscopix have partnered to develop an integrated electrophysiology and imaging system for the brain. // Stock Photo

Inscopix Inc., a brain mapping platform company in Palo Alto, Calif., and NeuroNexus Inc., a neurotechnology company pioneering high-capacity implantable neural interfaces in Ann Arbor, announced a collaboration to develop the world’s first integrated electrophysiology and imaging system.

The system will enable deeper insights into brain function and advance the development of novel therapeutics and medical devices toward addressing neurodegenerative, psychiatric, and brain trauma disorders.

The system will use Inscopix’s imaging expertise, miniaturized microscope-based brain mapping platform, and the ability to develop multimodal solutions. NeuroNexus will bring industry-leading knowledge and expertise in miniaturized systems for electrophysiological recording and stimulation.

“Integration of these platforms will enable completely new insights in how the brain functions in normal state and diseased state, and aid in the discovery and development of novel pharmaceutical drug strategies to combat brain disorders,” says Kunal Ghosh, CEO at Inscopix

The companies plan to offer an early access program in the future, when scientists and clinical researchers will be able to correlate neural circuit dynamics with brain network state.

Neural circuit dynamics refers to the patterns of nerve cell electrical and chemical activity in which information is created, manipulated, and stored, according to the Princeton Neuroscience Institute’s Bezos Center for Neural Circuit Dynamics.

Functional connectivity is the temporal correlation between spatially remote neurophysiological events according to a paper, according to an article published in Wiley Analytical Science Journals. In other words, activity in brain regions that isn’t correlated physically, but by timing.

“This innovative, multi-modal system will provide a powerful window into brain function over remarkable spatial and temporal scales that will accelerate neuroscience research and development of new clinical neurotechnologies,” says Daryl Kipke, CEO of NeuroNexus.

With almost 200 peer-reviewed publications validating its innovative brain circuitry mapping technology, Inscopix allows the neuroscience research community to advance science while bringing therapeutics to patients with difficult-to-treat brain disorders.

NeuroNexus’ team of neuroscientists and neuroengineers aims to create neurotechnology that provides life science researchers with confidence in the data from the neural interface to the user interface and beyond.

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